Side effects of LDN are few and have not been commonly reported.

Most common side effects have been:

• VIVID dreams are common, usually only lasting a few days; if these become bothersome for the patients, the time of dose could be adjusted to the am

• Stomach cramps/diarrhea – rare

• Increased thyroid sensitivity; medication may need adjustment

• Flu-like symptoms; if longer than 24 hours, the dose may be cut in half until symptoms resolve